Liferna 2.0 Website Launch

We’re refreshing the Liferna website with updated content, enhanced functionality, and a stronger focus on our science, pipeline, and vision. Stay tuned for more updates.

Developing Life-Changing Medicines to Treat Autoimmune and Fibrotic Diseases with No Cure

Pioneering innovative platform technology to deliver novel targeted products for Patients.

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Our Vision

Make a transformative difference in the lives of patients battling with autoimmune and fibrotic diseases with no cure.

Our Mission

Develop and launch first-in-class safe and effective products globally to treat patients with autoimmune and fibrotic diseases.

Our Approach

Developing Validated Platforms. Targeting Disease-Modifying Pathways. Accelerating Products to Market.

Liferna combines scientific excellence with strategic development, leveraging a unique and proprietary platform technology, and novel targeted drug delivery approaches to create transformative therapies for autoimmune and fibrotic diseases. By focusing on validated disease-modifying pathways, Liferna is accelerating the development of breakthrough treatments that address unmet patient needs and bring innovative products to the market rapidly.

Our Approach

Precision Medicine and Execution are at The Core of Our Mission.

At Liferna, we believe that understanding disease biology is only part of the solution—equally critical is delivering therapies precisely where they’re needed. Our approach pairs a deep knowledge of validated disease-modifying pathways with novel targeted drug delivery and our proprietary platform technology solutions, enabling us to reach the right cells and tissues with greater accuracy and minimize unintended off-target effects. With precision medicine and execution at the core of our mission, we are not only advancing a new generation of safe and effective therapies for autoimmune and fibrotic conditions but also navigating the regulatory process for first-in-class product, and accelerating development from the clinic to the market.

Our Focus

The Impact of Autoimmune and Fibrotic Diseases on Patients and Caregivers: A Call for Safer and More Effective Treatments

Autoimmune and fibrotic diseases, such as systemic sclerosis (SSc), profoundly affect patients and their caregivers, leading to significant physical, emotional, and economic burdens. Affecting more than 2.5 million people globally, SSc is a rare and devastating autoimmune disease characterized by immune system dysregulation, tissue fibrosis, and vascular dysfunction, resulting in the hardening and tightening of the skin and, in many cases, internal organ damage.

Our Focus

Impact on Patients

For patients, the manifestations of systemic sclerosis (SSc) can severely impair daily activities and quality of life. The thickening of the skin, particularly on the hands and feet, can limit mobility and dexterity, making simple tasks challenging. Pulmonary complications, such as interstitial lung disease (ILD), are common and can lead to decreased lung function, resulting in fatigue and breathlessness. Beyond the lungs and skin, SSc often affects internal organs, with serious consequences. Cardiac involvement may include myocardial fibrosis, arrhythmias, and pericardial effusion, which can lead to heart failure or sudden cardiac death. These manifestations may be asymptomatic in early stages but become life-threatening as the disease progresses. Renal involvement, notably scleroderma renal crisis (SRC), is a potentially life-threatening complication characterized by acute hypertension and rapidly progressive renal failure, requiring prompt medical intervention.

*Pictures of hands provided by Dinesh Khanna, MD, MSc

Our Focus

The Hidden Strain of GI Symptoms

Gastrointestinal manifestations are among the most frequent and can affect any part of the GI tract, from the esophagus to the rectum. Patients often experience difficulty swallowing, acid reflux, bloating, malabsorption, and altered bowel habits, including severe constipation or diarrhea. These symptoms not only contribute to discomfort but also nutritional deficiencies and weight loss.

Our Focus

Impact on Caregivers

Caregivers of individuals with SSc also face considerable challenges. They often assist with daily activities, manage medical appointments, and provide emotional support. This responsibility can lead to caregiver fatigue, financial strain, and social isolation. The progressive nature of SSc means that caregiving demands may increase over time, necessitating ongoing adjustments and support.

Our Focus

Impact on Patients

Beyond physical symptoms, SSc patients frequently experience psychological distress, including depression and anxiety, stemming from the chronic nature of the disease and its visible effects on appearance. The unpredictability of disease progression further exacerbates emotional strain, highlighting the need for comprehensive care approaches that address both physical and mental health aspects.

Our Approach

Improving Lives Through Innovation

At Liferna Biotech, we are committed to pioneering research and development efforts aimed at discovering and delivering more effective treatments for autoimmune and fibrotic diseases. Our goal is to alleviate the multifaceted burdens faced by patients and their caregivers, ultimately enhancing their quality of life and providing hope for a healthier future.

Our Pipeline

Pipeline Overview

Pipeline Update

Our development pipeline is currently being updated to reflect recent strategic portfolio advancements and program prioritization. An updated pipeline overview will be available with the relaunch of our website.

Thank you for your interest in Liferna as we continue to advance innovative medicines for patients worldwide.

Our Team

Management Team